Instructions of Cortex Ilicis Rotundae

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Name: Cortex Ilicis Rotundae(Royal Icing)
Resource: The bark of Ilex rotunda Thunb.,family Aquifoliaceae.
Characteristic: Crude drugs somewhat curved in pieces,varying in size,0.3-1.0 cm   thick,crustaceous,epidermis grey-white to grey-yellow,coarse;endodermis brown,with   longitudinal striae;section showing flat and granular,green periderm seen when the cork is stripped of,slightly aromatic in odour.Bitter in taste and cold in nature.
Pharmacodynamics: 1.Purge the sthenic fire and detoxify:For common cold with high fever,sorethroat,conjunctival congestion,skin infection,cholecystitis,etc.External use for burns. 2.Clear away heat and dampness:For diarrhea and dysentery of dampnessheat type. 3.Cool the blood and stop bleeding:For hematemesis,hemoptysis,and hematochezia due to blood-heat. 4.Alleviate pain:For abdominal pain due to dampness-heat or stomachheat,also for arthralgia of wind-dampness-heat type.
Pharmacological: 1.Hemostatic.Ilexanin B shortens the blood coagulation time in vitro. 2.Causing vasoconstriction in experimental animals.
Usage: Decoction:6-15g.External application:30-50% solution.
the effects of Cortex Ilicis Rotundae (CIR) on Cardiovascular Pharmacology are studied. The results show that ethyl alcohol extract of CIR can reduce coronary blood flow, weaken myocardial contractility, slow down heart rates, prolong survival time of mice and prevent arrhythmias, the roles of CIR decoction are similar to ethyl alcohol extract, but it is not markable on heart rates and myocardial contractility.

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